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Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

✍ Scribed by Minokoshi, Yasuhiko; Kim, Young-Bum; Peroni, Odile D.; Fryer, Lee G. D.; Müller, Corinna; Carling, David; Kahn, Barbara B.

Book ID
109802782
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
201 KB
Volume
415
Category
Article
ISSN
0028-0836

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## Abstract The aim of this study was to investigate the chronic effects of palmitate on fatty acid (FA) oxidation, AMPK/ACC phosphorylation/activation, intracellular lipid accumulation, and the molecular mechanisms involved in these processes in skeletal muscle cells. Exposure of L6 myotubes for 8