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Leptin reduces Alzheimer’s disease-related tau phosphorylation in neuronal cells

✍ Scribed by Steven J. Greco; Sraboni Sarkar; Jane M. Johnston; Xiongwei Zhu; Bo Su; Gemma Casadesus; J. Wesson Ashford; Mark A. Smith; Nikolaos Tezapsidis

Book ID
116297431
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
501 KB
Volume
376
Category
Article
ISSN
0006-291X

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## Abstract Tau function is regulated by phosphorylation, and abnormal tau phosphorylation in neurons is one of the key processes associated with development of Alzheimer's disease and other tauopathies. In this study we provide evidence that phospholipid transfer protein (PLTP), one of the main li