Leptin-mediated cytokine release and migration of eosinophils: Implications for immunopathophysiology of allergic inflammation

Activation of human bronchial epithelial

Activation of human bronchial epithelial cells by inflammatory cytokines IL-27 and TNF-α: Implications for immunopathophysiology of airway inflammation

✍ Ju Cao; Chun K. Wong; Yibing Yin; Christopher W.K. Lam 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 692 KB

## Abstract Interleukin (IL)‐27 is a member of IL‐6/IL‐12 family cytokines produced by antigen‐presenting cells in immune responses. IL‐27 can drive the commitment of naive T cells to a T helper type 1 (Th1) phenotype and inhibit inflammation in later phases of infection. Human bronchial epithelial