Leptin is a growth factor for human colon cancer cells
β Scribed by Hardwick, James C.H.; Van Den Brink, Gijs R.; Van Deventer, Sander J.H.; Peppelenbosch, Maikel P.
- Book ID
- 124120978
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 191 KB
- Volume
- 120
- Category
- Article
- ISSN
- 0016-5085
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## Abstract Human colon cancer cells produce and secrete a variety of polypeptide growth factors. The functional role of these growth factors, however, is poorly understood. Though the secretion of epidermal growth factor (EGF)βlike activity and EGFβrelated molecules by human colon cancer cells in
## Abstract Human colon cancer cell lines express epidermal growth factor (EGF) mRNA, secrete EGF and may respond to it __via__ the cellβsurface EGF receptor (EGFR). Expression of these molecules in human colon and colon tumor, however, is not clear. Reverse transcriptionβpolymerase chain reaction