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Leptin Enhances the Release of Cytokines by Peripheral Blood Mononuclear Cells from Relapsing Multiple Sclerosis Patients

✍ Scribed by Giovanni Frisullo; Francesco Angelucci; Massimiliano Mirabella; Marcella Caggiula; Katia Patanella; Viviana Nociti; PietroAttilio Tonali; AnnaPaola Batocchi


Book ID
111591960
Publisher
Springer
Year
2004
Tongue
English
Weight
108 KB
Volume
24
Category
Article
ISSN
0271-9142

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## Abstract Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system, and it is considered to be a T helper 1 (Th1) cell‐mediated autoimmune disease. T‐bet has been identified as a key transcription factor for the development of Th1 cells and the inducti