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Lentivirus-mediated RNAi knockdown of insulin-like growth factor-1 receptor inhibits growth, reduces invasion, and enhances radiosensitivity in human osteosarcoma cells

โœ Scribed by Yin-He Wang; Zhao-Xia Wang; Yong Qiu; Jin Xiong; Yi-Xin Chen; Deng-Shun Miao; Wei De


Publisher
Springer
Year
2009
Tongue
English
Weight
501 KB
Volume
327
Category
Article
ISSN
0300-8177

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โœ Ryszard Braczkowski; Andrew V. Schally; Artur Plonowski; Jozsef L. Varga; Kate G ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 331 KB ๐Ÿ‘ 2 views

## Abstract ## BACKGROUND Antagonists of growth hormoneโ€releasing hormone (GHโ€RH) can inhibit the proliferation of various tumors either indirectly through the suppression of the pituitary growth hormone/hepatic insulinโ€like growth factor I (__IGFโ€I__) axis and the lowering of serum __IGFโ€I__ conc