✦ LIBER ✦

Lentivirus-mediated platelet-derived factor VIII gene therapy in murine haemophilia A

✍ Scribed by Q. SHI; D. A. WILCOX; S. A. FAHS; J. FANG; B. D. JOHNSON; L. M. DU; D. DESAI; R. R. MONTGOMERY

Book ID: 109151931
Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 872 KB
Volume: 5
Category: Article
ISSN: 1538-7933
DOI: 10.1111/j.1538-7836.2007.02346.x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Therapeutic levels of human Factor VIII

Therapeutic levels of human Factor VIII in mice implanted with encapsulated cells: potential for gene therapy of haemophilia A

✍ Carmen García-Martín; Marinee K. L. Chuah; An Van Damme; Kelly E. Robinson; Beat 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 129 KB

## Abstract ## Background A gene therapy delivery system based on microcapsules enclosing recombinant cells engineered to secrete a therapeutic protein has been evaluated. The microcapsules are implanted intraperitoneally. In order to prevent cell immune rejection, cells are enclosed in non‐antige

Shear-induced platelet-derived growth fa

Shear-induced platelet-derived growth factor gene expression in human endothelial cells is mediated by protein kinase C

✍ Hsyue-Jen Hsieh; Nan-Qian Li; John A. Frangos 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 832 KB

Our previous studies have shown that steady shear stress causes a transient increase of platelet-derived growth factor (PDGF) A and B chain mRNA levels in human umbilical vein endothelial cells (HUVEC). In the present study, we elucidated the signaling pathway of shear stress in HUVEC by examining t