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Lentivirus-mediated gene silencing of KLF8 reduced the proliferation and invasion of gastric cancer cells

✍ Scribed by Gang Chen, Wenjun Yang, Weidong Jin, Yi Wang, Chonglin Tao…


Book ID
120751125
Publisher
Springer
Year
2012
Tongue
English
Weight
376 KB
Volume
39
Category
Article
ISSN
0301-4851

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High‐mobility group box 1 (HMGB1) is a multifunctional protein with intranuclear and extracellular functions. Although HMGB1 is overexpressed in approximately 85% of gastric cancers, the role of HMGB1 in gastric cancer biology remains unclear. In this study, we investigate the effect of downregulati