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Lens opacity in patients with hypercholesterolemia and ischaemic heart disease

✍ Scribed by Markku Leino; Kalevi Pyörälä; Seppo Lehto; Arto Rantala

Publisher
Springer-Verlag
Year
1992
Tongue
English
Weight
368 KB
Volume
80
Category
Article
ISSN
0012-4486

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✦ Synopsis

Lens opacity studies were performed using an electronic Lens Opacity Meter (Interzeag Opacity Lensmeter 701) in a population (n = 321) with ischaemic heart disease. These patients are participating in a trial targetting at the reduction of mortality and incidence of myocardial infarction using a cholesterol-lowering drug, simvastatin. A separate study to evaluate the reliability of the method showed good reproducibility. Repeated measurements after a short time-interval (2-10 days) gave statistically lower opacity values either due to a change in lens transparency or perhaps a change in pigment and cell dispersion in the acqueous caused by repeated mydriasis. Lens opacity values showed a highly significant positive correlation to age. Serum cholesterol, systolic blood pressure and smoking habits showed no significant correlations to the levels of lens opacity when adjustments for age were made.

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