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Lenalidomide: in vitro evaluation of the metabolism and assessment of cytochrome P450 inhibition and induction

โœ Scribed by Gondi Kumar; Henry Lau; Oscar Laskin


Publisher
Springer
Year
2008
Tongue
English
Weight
243 KB
Volume
63
Category
Article
ISSN
0344-5704

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The role of different cytochrome P450 is
โœ Testai, Emanuela ;De Curtis, Valentina ;Gemma, Simonetta ;Fabrizi, Laura ;Gervas ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 111 KB ๐Ÿ‘ 2 views

The two CHCl3 activation pathways have been studied in incubations at different oxygenation conditions with hepatic microsomes from control Sprague Dawley (SD) rats or SD rats treated with different cytochrome P450 inducers (acetone, phenobarbital, pyrazole, dexamethasone, and beta-naphthoflavone).