Solution structure of TsKapa, a charybdo
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E. Blanc; C. Lecomte; J. Van Rietschoten; J.M. Sabatier; H. Darbon
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Article
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1997
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John Wiley and Sons
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English
⚖ 802 KB
TsKapa (TsK), purified from the Buthidae Tityus serrulatus is a very high potent ligand for small-conductance apaminsensitive calcium-activated potassium channels (SK). It is able to efficiently compete with apamin for binding on this channel (K 0.5 ؍ 0.3 nM) [Legros, C. et al., FEBS Lett. 390:81-