𝔖 Bobbio Scriptorium
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Leigh disease with deficiency of lipoamide dehydrogenase: Treatment failure with dichloroacetate

✍ Scribed by William J. Craigen


Book ID
116153883
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
332 KB
Volume
14
Category
Article
ISSN
0887-8994

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Pyruvate dehydrogenase activity is not d
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In autopsied brain tissue from three cases with Leigh disease (subacute necrotizing encephalomyelitis, SNE) and controls, the activity of pyruvate dehydrogenase complex (PDHC) was determined under different conditions. It was found to be at the control level or increased, but not deficient. The acti