Leflunomide/chloroquin combination therapy in rheumatoid arthritis: a pilot study
β Scribed by Bernhard Rintelen; Ingrid Andel; Judith Sautner; Burkhard F. Leeb
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 78 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0770-3198
No coin nor oath required. For personal study only.
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## Objective: To report the safety and efficacy of leflunomide (lef) in combination with infliximab (inf) for the treatment of rheumatoid arthritis. ## Methods: In an open, multicenter, retrospective study, data were collected on the safety and efficacy of lef and inf. ## Results: Eighty-eight
Nineteen selected patients with severe, mostly systemic onset, juvenile rheumatoid arthritis were treated with methotrexate (MTX) for an average of 10.5 months. Twelve patients showed statistically significant improvement, as measured by the number of affected, swollen, tender, and functionally impa