## Objective: To determine whether treatment with leflunomide (lef), methotrexate (mtx), or sulfasalazine (ssz) for 6-12 months retards progression of radiographic damage and to identify clinical variables that correlate with radiographic progression. ## Methods: Radiographs of the hands and feet
✦ LIBER ✦
Leflunomide in the treatment of patients with early rheumatoid arthritis—results of a prospective non-interventional study
✍ Scribed by Herbert Kellner; Klaus Bornholdt; Gert Hein
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 144 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0770-3198
No coin nor oath required. For personal study only.
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## Abstract ## Objective To investigate the efficacy and safety of leflunomide beyond 2 years in a multinational, open‐label extension of 2 phase III double‐blind studies. ## Methods Patients with rheumatoid arthritis (RA) who received leflunomide (100 mg/day for 3 days, 10 mg/day or 20 mg/day t