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Leading-edge research: PtdIns(3,4,5)P3 and directed migration

✍ Scribed by Franca-Koh, Jonathan; Kamimura, Yoichiro; Devreotes, Peter N.


Book ID
109911267
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
202 KB
Volume
9
Category
Article
ISSN
1465-7392

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## Abstract The SH2 domain containing inositol 5‐phosphatase 2 (SHIP2) belongs to the family of the mammalian inositol polyphosphate 5‐phosphatases. The two closely related isoenzymes SHIP1 (or SHIP) and SHIP2 contain a N‐terminal SH2 domain, a catalytic domain, potential PTB domain‐binding sites (