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Lead exposure activates nuclear factor kappa B, activator protein-1, c-Jun N-terminal kinase and caspases in the rat brain

✍ Scribed by Govindarajan T Ramesh; Sunil K Manna; Bharat B Aggarwal; Arun L Jadhav


Book ID
119537096
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
454 KB
Volume
123
Category
Article
ISSN
0378-4274

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## Abstract The roles of the mitogen‐activated kinase protein (MAPK) pathway, nuclear factor‐kappa B (NF‐κB), and activator protein‐1 (AP‐1) in cellular responses to growth factors and mitogen are well established. However, the manner by which these proliferative pathways are affected by the tumor