## Abstract Previous reports have recently shown the prototypic neurotoxicant, lead, to induce apoptosis in the brains of developing organisms. In the current study, timedβpregnant rats were exposed to lead acetate (0.2% in the drinking water) 24 h following birth at postnatal day 1 (PND 1). Dams a
Lead Affects Apoptosis and Related GeneXIAPandSmacExpression in the Hippocampus of Developing Rats
β Scribed by Junxiao Liu; Dai Han; Yan Li; Liangkai Zheng; Chengwu Gu; Zhongxian Piao; William W. Au; Xijin Xu; Xia Huo
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 295 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0364-3190
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## Abstract Postnatal exposure (from the second day after birth to 30 days) of rat pups to low levels of lead acetate (50 mg/kg body weight/day), administered by gastric intubation, yielded a maximum blood level of 76.1ΞΌg/100 ml, at day 15 of age. Cerebellar and hippocampal lead contents were 8.67ΞΌ