Familial hypercholesterolemia (FH) is an inherited disorder of lipoprotein metabolism involving mutations in the LDL receptor (LDL-R). Patients with mutation in one (heterozygous) or both (homozygous) genes have markedly elevated LDL cholesterol and are at increased risk for coronary heart disease (
LDL-apheresis in pediatric patients with severe hyperlipoproteinemia
β Scribed by C. Stefanutti; A. Vivenzio; C. Colombo; S. Di Giacomo; B. Mazzarella; A. Berni; A. Nigri; N. Koga
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 107 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0733-2459
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As therapeutic apheresis becomes more and more popular, its use in children has remained limited. in most cases, the reports that do exist are either brief abstracts or a notation in a larger group of adult patients.
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Angiotensin-converting-enzyme (ACE) inhibitors reduce morbidity and mortality in patients with chronic heart failure and systolic left-ventricular dysfunction, as well as in patients who have had a myocardial infarction . These drugs, in familial hypercholesterolemic (FH) patients treated with low-d
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