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LC–MS–MS Study of the Pharmacokinetics of a 9-β-Dihydro-9,10-O-acetal Derivative of Docetaxel in Rats and Beagle Dogs

✍ Scribed by Xiaoling Hu; Jianguo Sun; Guangji Wang; Xiaoyan Zhu; Gang Hao; Yongchuan Gu; Frederik B. Pruijn


Book ID
111791173
Publisher
Springer
Year
2008
Tongue
English
Weight
142 KB
Volume
68
Category
Article
ISSN
0009-5893

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✍ Julia Jung; Markus R. Meyer; Hans H. Maurer; Christian Neusüß; Wolfgang Weinmann 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 215 KB

## Abstract In __Cannabis sativa__, Δ9‐Tetrahydrocannabinolic acid‐A (Δ9‐THCA‐A) is the non‐psychoactive precursor of Δ9‐tetrahydrocannabinol (Δ9‐THC). In fresh plant material, about 90% of the total Δ9‐THC is available as Δ9‐THCA‐A. When heated (smoked or baked), Δ9‐THCA‐A is only partially conver