LC/MS: A Practical User's Guide

✍ Scribed by Marvin McMaster

• Publisher: Wiley-Interscience
• Year: 2005
• Tongue: English
• Leaves: 168
• Category: Library

✦ Synopsis

A practical guide to using and maintaining an LC/MS system The combination of liquid chromatography (LC) and mass spectrometry (MS) has become the laboratory tool of choice for a broad range of industries that require the separation, analysis, and purification of mixtures of organic compounds. LC/MS: A Practical User's Guide provides LC/MS users with an easy-to-use, hands-on reference that focuses on the practical applications of LC/MS and introduces the equipment and techniques needed to use LC/MS successfully. Following a thorough explanation of the basic components and operation of the LC/MS system, the author presents empirical methods for optimizing the techniques, maintaining the instrumentation, and choosing the appropriate MS or LC/MS analyzer for any given problem. LC/MS covers everything users need to know about:

• The latest equipment, including quadrupole, time-of-flight, and ion trap analyzers
• Cutting-edge processes, such as preparing HPLC mobile phases and samples; handling and maintaining a wide variety of silica, zirconium, and polymeric separation columns; interpreting and quantifying mass spectral data; and using MS interfaces
• Current and future applications in the pharmaceutical and agrochemical industries, biotechnology, clinical research, environmental studies, and forensics

An accompanying PowerPoint® slide-set on CD-ROM provides vital teaching tools for instructors and new equipment operators. Abundantly illustrated and easily accessible, the text is designed to help students and practitioners acquire optimum proficiency in this powerful and rapidly advancing analytical application.

✦ Table of Contents

fmatter......Page 1
ch1......Page 11
ch2......Page 19
ch3......Page 31
ch4......Page 43
ch5......Page 51
ch6......Page 60
ch7......Page 67
ch8......Page 78
ch9......Page 92
ch10......Page 101
ch11......Page 108
ch12......Page 115
ch13......Page 123
ch14......Page 130
app1......Page 134
app2......Page 142
app3......Page 146
app4......Page 152
app5......Page 158
index......Page 160