LC–high resolution MS in environmental analysis: from target screening to the identification of unknowns

An algorithm for thorough background sub

An algorithm for thorough background subtraction from high-resolution LC/MS data: application to the detection of troglitazone metabolites in rat plasma, bile, and urine

✍ Haiying Zhang; Li Ma; Kan He; Mingshe Zhu 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 359 KB

## Abstract Interferences from biological matrices remain a major challenge to the __in vivo__ detection of drug metabolites. For the last few decades, predicted metabolite masses and fragmentation patterns have been employed to aid in the detection of drug metabolites in liquid chromatography/mass