LC-MS in Drug Bioanalysis || Impact of Sampling Paper/Cards on Bioanalytical Quantitation via Dried Blood Spots by Liquid Chromatography-Mass Spectrometry
✍ Scribed by Xu, Q. Alan; Madden, Timothy L.
- Book ID
- 118197332
- Publisher
- Springer US
- Year
- 2012
- Tongue
- English
- Weight
- 543 KB
- Edition
- 2012
- Category
- Article
- ISBN
- 1461438284
No coin nor oath required. For personal study only.
✦ Synopsis
Clinical pharmacology plays an important role in today’s medicine. Due to the high sensitivity, selectivity, and affordability of a mass spectrometer (MS), the high performance liquid chromatography – mass spectrometry (LC-MS) analytical technique is widely used in the determination of drugs in human biological matrixes for clinical pharmacology. Specifically, LC-MS is used to analyze: anticancer drugs antidementia drugs antidepressant drugs antiepileptic drugs antifundal drug antimicrobial drugs antipsychotic drugs antiretroviral drugs anxiolytic/hypnotic drugs cardiac drugs drugs for addiction immunosuppressant drugs mood stabilizer drugs This book will primarily cover the various methods of validation for LC-MS techniques and applications used in modern clinical pharmacology.