Advances in liquid chromatography-mass spectrometry (LC-MS) can be used to measure steroid hormone metabolites in vitro and in vivo. We find that LC-electrospray ionization (ESI)-MS using a LCQ ion trap mass spectrometer in the negative ion mode can be used to monitor the product profile that result
LC-MS in Drug Bioanalysis || Applications of Mass Spectrometry in Analyses of Steroid Hormones
β Scribed by Xu, Q. Alan; Madden, Timothy L.
- Book ID
- 119999815
- Publisher
- Springer US
- Year
- 2012
- Tongue
- English
- Weight
- 642 KB
- Edition
- 2012
- Category
- Article
- ISBN
- 1461438284
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β¦ Synopsis
Clinical pharmacology plays an important role in todayβs medicine. Due to the high sensitivity, selectivity, and affordability of a mass spectrometer (MS), the high performance liquid chromatography β mass spectrometry (LC-MS) analytical technique is widely used in the determination of drugs in human biological matrixes for clinical pharmacology. Specifically, LC-MS is used to analyze: anticancer drugs antidementia drugs antidepressant drugs antiepileptic drugs antifundal drug antimicrobial drugs antipsychotic drugs antiretroviral drugs anxiolytic/hypnotic drugs cardiac drugs drugs for addiction immunosuppressant drugs mood stabilizer drugs This book will primarily cover the various methods of validation for LC-MS techniques and applications used in modern clinical pharmacology.
π SIMILAR VOLUMES
Clinical pharmacology plays an important role in todayβs medicine. Due to the high sensitivity, selectivity, and affordability of a mass spectrometer (MS), the high performance liquid chromatography β mass spectrometry (LC-MS) analytical technique is widely used in the determination of drugs in huma
Clinical pharmacology plays an important role in todayβs medicine. Due to the high sensitivity, selectivity, and affordability of a mass spectrometer (MS), the high performance liquid chromatography β mass spectrometry (LC-MS) analytical technique is widely used in the determination of drugs in huma