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Laurencienyne, a new acetylenic cyclic ether from the marine red alga laurencia obtusa

✍ Scribed by Salvatore Caccamese; Roberto Azzolina; Eileen N. Duesler; Iain C. Paul; Kenneth L. Rinehart Jr.

Publisher: Elsevier Science
Year: 1980
Tongue: French
Weight: 201 KB
Volume: 21
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)92589-9

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✦ Synopsis

The structure and absolute stereochemistry of laurencienyne, a non-isoprenoid cyclic ether isolated from Laurencia obtusa, has been established by X-ray and spectroscopic studies. In our continuing effort to screen marine algae from Eastern Sicily for antimicrobial activity and to isolate the active components, we have investigated several species of the Laurencia genus (Rhodophyta)."' Laurencia obtusa (Huds.) Lamour., a widespread Mediterranean alga whose lipid extract inhibited Bacillus subtilis and Escherichia coli 2 -_--y was found to contain several halogenated sesquiterpenes3 and interest in this species has been sustained by

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