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Lateral phase separations in membranes

✍ Scribed by Shimshick, E. J. ;Kleemann, W. ;Hubbell, W. L. ;McConnell, H. M.


Publisher
Wiley (John Wiley & Sons)
Year
1973
Tongue
English
Weight
476 KB
Volume
1
Category
Article
ISSN
0091-7419

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✦ Synopsis


Abstract

Lateral phase separations of phospholipids in both bacterial membranes and model membrane systems (phospholipid bilayers) can be studied using spin labels. Temperature–composition phase diagrams have been determined for binary mixtures of lipids dispersed in excess water by measurements of changes in the fluidity of the membranes as a function of temperature. These results have been used to interpret similar fluidity changes in bacterial membranes. There is evidence that the coexistence of fluid and solid lipid domains facilitates transport through membranes.


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