Previous reports have observed a fall in antithrombin III (AT III) concentration in patients receiving L-asparaginase as part of acute lymphatic leukaemia (ALL) induction therapy. The aim of this study was to define any qualitative changes in AT III that might arise during the course of L-asparagina
✦ LIBER ✦
Latent onset of clinical pancreatitis in children receiving l-asparaginase therapy
✍ Scribed by Robert M. Weetman; Robert L. Baehner
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- English
- Weight
- 471 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0008-543X
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## Abstract A novel assay for the determination of l‐asparaginase activity in human plasma is described that is based on the HPLC quantitation of l‐aspartic acid produced during enzyme incubation. Methods for monitoring l‐asparagine depletion are also described. Chromatography of l‐aspartic acid, l