Latent autoimmune diabetes in adults (LADA) should be less latent
β Scribed by S. Fourlanos; F. Dotta; C. J. Greenbaum; J. P. Palmer; O. Rolandsson; P. G. Colman; L. C. Harrison
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 119 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0012-186X
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π SIMILAR VOLUMES
## Abstract ## Background Some type 1 diabetic patients do not require insulin at diagnosis of diabetes, and they progress to insulin dependence only after several years (latent autoimmune diabetes in adults). However, not all patients with latent autoimmune diabetes in adults progress to insulin
Background LADA is thought to result from the chronic autoimmune destruction of the insulin-producing pancreatic Ξ² cells. In addition to antidiabetic effects, the newly developed insulin sensitizer-thiazolidinediones have the potential to increase the insulin content of islet cells by downregulating