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Latency and reactivation of a thymidine kinase-negative bovine herpesvirus 1 deletion mutant

✍ Scribed by C. A. Whetstone; J. M. Miller; B. S. Seal; L. J. Bello; W. C. Lawrence


Publisher
Springer Vienna
Year
1992
Tongue
English
Weight
691 KB
Volume
122
Category
Article
ISSN
1432-8798

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## Abstract A BK virus (BKV) expression vector, specific for human cells, was engineered to express antisense human immunodeficiency virus type 1 (HIV‐1) __tat__ cDNA (__tat__‐AS) or a __tat__ mutant in cysteine 22 (__tat__22). Cysteine residues in the cysteine‐rich domain of __tat__ are necessary