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Late reversibility of chronic ifosfamide-associated nephrotoxicity in a child

✍ Scribed by Ashraf, M. Shamvil; Skinner, Roderick; English, Martin W.; Craft, Alan W.; Pearson, Andrew D.J.

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 60 KB
Volume: 28
Category: Article
ISSN: 0098-1532
DOI: 10.1002/(sici)1096-911x(199701)28:1<62::aid-mpo12>3.0.co;2-c

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✦ Synopsis

Although reversibility of acute ifosfamide-in-famide) for prostatic rhabdomyosarcoma. Furduced nephrotoxicity is well documented, there ther investigation confirmed glomerular and is a paucity of data concerning the long-term generalised tubular dysfunction with a Fanconi outcome of chronic renal toxicity, and full re-syndrome. However, serial investigation over covery from established damage has not been the next 4 years revealed complete and susreported. A 4-year-old boy presented with hypo-tained recovery of this chronic nephrotoxicity. phosphatemic rickets 9 months after completion ᮊ 1997 Wiley-Liss, Inc. of combination chemotherapy (including ifos-

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