Late relapse and mortality in stage I large bowel cancer
β Scribed by George J. Hill; Bimal C. Ghosh
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 695 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0022-4790
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
The outcome was determined for patients with Stage I cancers of the large bowel (colon, rectum, and anus) who were treated from 1982β1989. In 119 consecutive patients, the 5βyear survival was approximately 70% (72% by the absolute direct method; 67% by the actuarial life table method). Although the overall 5βyear survival was similar to numerous other published reports, it was disturbing to observe that 41 % of the living patients had relapsed. Furthermore, although 88/119 (67%) were alive at last report, 2β7 years after treatment, only 23 (19%) were believed to be free of cancer. We conclude that followβup for more than 5 years and the assessment of diseaseβfree survival are required to evaluate the outcome from Stage I large bowel cancer. Β© 1992 WileyβLiss, Inc.
π SIMILAR VOLUMES
The purpose of this study was to determine whether cultured colonic adenoma and carcinoma cells undergo apoptosis (programmed cell death) in vitro and whether specific growth and dietary factors, thought to be involved in the control of growth and differentiation of human colonic cells, could induce