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Late recurrences of gastrointestinal stromal tumours (GISTs) after 5

✍ Scribed by Margherita Nannini; Guido Biasco; Maria Caterina Pallotti; Monica Di Battista; Donatella Santini; Paola Paterini; Alessandra Maleddu; Anna Mandrioli; Cristian Lolli; Maristella Saponara; Valerio Di Scioscio; Maurizio Zompatori; Fausto Catena; Pietro Fusaroli; Angelo Paolo Dei Tos; Maria Abbondanza Pantaleo

Book ID
107577419
Publisher
Springer US
Year
2011
Tongue
English
Weight
159 KB
Volume
29
Category
Article
ISSN
1357-0560

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## Abstract ## BACKGROUND. Gastrointestinal stromal tumor (GIST) is the most frequent sarcoma of the intestinal tract and often shows constitutive activation of either the KIT or PDGFRA receptor tyrosine kinases because of gain‐of‐function mutation. Although the efficacy of tyrosine kinase inhibit