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Late-onset warfarin-induced skin necrosis: case report and review of the literature

โœ Scribed by Essex, D.W.; Wynn, S.S.; Jin, D.K.

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
153 KB
Volume
57
Category
Article
ISSN
0361-8609

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โœฆ Synopsis

Warfarin-induced skin necrosis is a rare complication of therapy with warfarin or other coumarin derivatives. When it occurs it usually appears 3 to 6 days after initiation of therapy and almost always between days 1 and 10. We report a case of late-onset (16 days after initiation of therapy) warfarin-induced skin necrosis and review the literature on this rarely reported variant of warfarin-induced skin necrosis. The skin lesion in our patient was not associated with either deficiency of protein C or resistance to activated protein C. Am.

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