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Late onset chronic mucocutaneous candidiasis with lymphoma and specific serum inhibitory factor

✍ Scribed by Iris K. Aronson; Christian H. L. Rieger; Keyoumars Soltani; Vladimir Tkalcevic; Wing C. Chan; Allan L. Lorincz; Gregory Matz


Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
763 KB
Volume
43
Category
Article
ISSN
0008-543X

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✦ Synopsis


A patient with late onset chronic mucocutaneous candidiasis developed lymphocytic lymphoma. A specific inhibitor of in vitro lymphoproliferative responses to candidal antigen was detected in her serum which persisted following clinical remission of candidiasis after combined amphotericin-B and 5-Fluorocystosine therapy. It is unclear whether the combined therapy was exclusively anticandidal, nonspecific immunostimulant or cytotoxic affecting the underlying incipient lymphoma.