✦ LIBER ✦

Late Expression of Nitroreductase in an Oncolytic Adenovirus Sensitizes Colon Cancer Cells to the Prodrug CB1954

✍ Scribed by Lukashev, Alexander N.; Fuerer, Christophe; Chen, Ming-Jen; Searle, Peter; Iggo, Richard

Book ID: 127331171
Publisher: Mary Ann Liebert
Year: 2005
Tongue: English
Weight: 571 KB
Volume: 16
Category: Article
ISSN: 1043-0342
DOI: 10.1089/hum.2005.16.1473

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Sensitisation of human carcinoma cells t

Sensitisation of human carcinoma cells to the prodrug CB1954 by adenovirus vector-mediated expression of E. coli nitroreductase

✍ Sarah J. Weedon; Nicola K. Green; Iain A. McNeish; Moira G. Gilligan; Vivien Mau 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 163 KB

The enzyme nitroreductase from E. coli can reduce the weak, monofunctional alkylating agent 5-(aziridin-1-yl)-2,4dinitrobenzamide (CB1954) to a potent cytotoxic species that generates interstrand crosslinks in DNA. Nitroreductase therefore has potential as a "suicide enzyme" for cancer gene therapy,

Downregulation of survivin expression by

Downregulation of survivin expression by induction of the effector cell protease receptor-1 reduces tumor growth potential and results in an increased sensitivity to anticancer agents in human colon cancer

✍ Tetsuhisa Yamamoto; Yoshinobu Manome; Motoyuki Nakamura; Nobuhiko Tanigawa 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 450 KB

Combined effects of 5-Fluorouracil, Foli

Combined effects of 5-Fluorouracil, Folinic acid and Oxaliplatin on the expression of carcinoembryonic antigen in human colon cancer cells: pharmacological basis to develop an active antitumor immunochemotherapy

✍ Salvatore P Prete, Mario Turriziani… 📂 Article 📅 2008 🏛 BioMed Central 🌐 English ⚖ 392 KB