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Late effect of prenatal irradiation on the hippocampal histology and brain weight in adult mice

✍ Scribed by M. Hossain; M. Chetana; P. Uma Devi


Book ID
116551351
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
168 KB
Volume
23
Category
Article
ISSN
0736-5748

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Methotrexate was administered by intraperitoneal injection (100 mg/kg) to unirradiated mice, and to mice receiving varying doses of cranial irradiation. The animals were sacrificed 24 hours after injection, and methotrexate assays were performed on brain tissue. No methotrexate was detected in the