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Laser Raman spectroscopic studies of poly(r-cytidylic acid) and poly(r-adenylic acid) complexes with poly(L-lysine) and poly(L-arginine)

✍ Scribed by Luis A. Hernández; René S. Vieta; Tze-Chi Jao

Publisher
Wiley (John Wiley & Sons)
Year
1980
Tongue
English
Weight
345 KB
Volume
19
Category
Article
ISSN
0006-3525

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✦ Synopsis

Abstract

Complexes of polyribocytidylic acid and polyriboadenylic acid with poly(L‐lysine) and poly(L‐arginine) were studied by Raman spectroscopy. The backbones of both polynucleotides are distorted by poly(L‐arginine). On the other hand, poly(L‐lysine) could distort the backbone of polyriboadenylic acid but not that of polyribocytidylic acid. In general, poly(L‐arginine) can increase the order of the base stacking, while poly(L‐lysine) causes disordering in the base stacking.

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