## Abstract Hematoporphyrin derivativeโphotoradiation therapy (HPDโPRT) of human malignancy has been performed on 267 tumor sites in 50 patients. Tumor response has been assayed at 24 hours and one month following treatment with 625โ635 nm light from an argon laserโpumped dye laser. The majority of
Laser photoradiation therapy of cancer: Possible role of hyperthermia
โ Scribed by Dr. Michael W. Berns; Joan Coffey; Alan G. Wile
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 350 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0196-8092
No coin nor oath required. For personal study only.
โฆ Synopsis
Two patients were treated at 20 different tumor sites by hematoporphyrin derivative (HPD) photoradiation therapy (PRT). An infrared detector was used to record changes in surface temperature during laser exposure. A temperature rise of up to 4.9 degrees C was recorded for a total energy of 15-30 J/cm2 and less than 150 mW/cm2. For 508 mW/cm2 and 15-20 J/cm2 a temperature rise of 7.0 degrees C was detected. The results suggest a possible role of hyperthermia in HPD-PRT.
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Visual function for ten patients undergoing HPD-PRT was tested using 1) the Graham Field Eye Chart for distance vision, 2) pseudo-isochromatic plates for color vision, and 3) Amsler grid for changes in macular function. Whereas some increases and decreases in ocular function were observed, no clear
This update of the experience at the University of California at Irvine with laser photoradiation therapy (PRT) encompasses the period between May 1981 and June 1983. The results of treatment of 77 patients are reported (head and neck, 39; breast, 33; and lung 5). Head and neck cancer patients recei
## Abstract In this study, a novel magnetic degradable material was developed by adding Fe ions into DPโBioglass (Na~2~OโCaOโP~2~O~5~โSiO~2~) as thermoseed for hyperthermia cancer therapy under an alternating magnetic field. We have investigated the properties of developed magnetic DPโBioglass incl
## Abstract In a rabbit model, endometriotic lesions were utilized to study hematoporphyrin derivative (HPD) uptake and the effect of photoradiation using the gold vapor laser. Morphological studies confirmed successful induction of ectopic endometrial growth and the lesions displayed preferential