Reaction of HO. with Guanine Derivatives
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Luis P. Candeias; Steen Steenken
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Article
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2000
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John Wiley and Sons
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English
⚖ 189 KB
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The reaction of . OH with 2'deoxyguanosine yields two transient species, both identified as OH adducts (G . -OH), with strongly different reactivity towards O 2 , or other oxidants, or to reductants. One of these, identified as the OH adduct at the C-8 position (yield 17 % relative to . OH), reacts