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Laser doppler flowmetry for bone blood flow measurement: Correlation with microsphere estimates and evaluation of the effect of intracapsular pressure on femoral head blood flow

✍ Scribed by Dr. Marc F. Swiontkowski; S. Tepic; S. M. Perren; R. Moor; R. Ganz; B. A. Rahn

Publisher: Elsevier Science
Year: 1986
Tongue: English
Weight: 851 KB
Volume: 4
Category: Article
ISSN: 0736-0266
DOI: 10.1002/jor.1100040313

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✦ Synopsis

Laser Doppler flowmetry (LDF) was used to measure bone blood flow in the rabbit femoral head and femoral condyles. To correlate the LDF output signal blood cell flux to in vivo blood flow, simultaneous measurements using LDF and 85Sr-labeled microspheres were made in an adult rabbit model. There was no correlation between the two methods for blood flow in the femoral condyles and the correlation between the two methods for blood flow in the femoral head does not achieve statistical significance. An LDF signal of 0.4 V was approximately equal to a microsphere measured flow rate of 0.4 ml blood/g bone/min. The strength of the correlation in the latter case may have

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