Laryngeal cancer risk and common single nucleotide polymorphisms in nucleotide excision repair pathway genes ERCC1, ERCC2, ERCC3, ERCC4, ERCC5 and XPA
β Scribed by Lu, Baocai; Li, Jing; Gao, Qingzu; Yu, Wenfa; Yang, Qinghui; Li, Xiaoyu
- Book ID
- 122732278
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 218 KB
- Volume
- 542
- Category
- Article
- ISSN
- 0378-1119
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A deficiency in DNA repair is associated with increased cancer risk. Inter-individual variations in DNA repair capacity observed in humans may result from genetic polymorphisms in DNA repair genes. In order to provide a basis for future functional and molecular epidemiology studies on cancer suscept
## Abstract Laryngeal cancer is known to be associated with smoking and high alcohol consumption. Nucleotide excision repair (NER) plays a key role in repairing DNA damage induced by these exposures and might affect laryngeal cancer susceptibility. In a populationβbased caseβcontrol study including