Measurement of pediatric cancer patients' health-related quality of life (HRQL) in phase III randomized, controlled clinical trials is being recognized increasingly as an essential component in evaluating the comprehensive health outcomes of modern anti-neoplastic treatment protocols. Use of a brief
Laryngeal cancer in Egypt: Quality of life measurement with different treatment modalities
β Scribed by Ossama A. Hamid; Lobna M. El Fiky; Medani M. Medani; Ayman AbdelHady; Hanan H. Ali
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 472 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1043-3074
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β¦ Synopsis
Abstract
Background
Quality of life (QOL) reflects the need to assess the patient's overall sense of wellβbeing. A nonrandomized, prospective longitudinal study was conducted to evaluate QOL in Egyptian patients treated for laryngeal cancer.
Methods
In all, 60 newly diagnosed patients with laryngeal cancer were divided into 3 groups: surgical resection, radiotherapy, and combined therapy. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaires (EORTCβQLQ) were administered to the patients at 4 points: prior to treatment, during active treatment, and at 3 and 6 months after completion of treatment.
Results
All pretreatment scales were worse in the combined therapy group. The functional scales reached their lowest levels in all groups during active treatment. Radiotherapy group scales showed persistent slow recovery. There was striking prevalence of the financial difficulties score in all groups.
Conclusion
QOL measurement provides information to guide clinical decision making in patients treated for laryngeal carcinoma. Β© 2010 Wiley Periodicals, Inc. Head Neck, 2011
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