✦ LIBER ✦

Larmor frequency selective model free analysis of protein NMR relaxation

✍ Scribed by David M. LeMaster

Book ID: 104659754
Publisher: Springer Netherlands
Year: 1995
Tongue: English
Weight: 919 KB
Volume: 6
Category: Article
ISSN: 0925-2738
DOI: 10.1007/bf00197636

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✦ Synopsis

The Lipari Szabo dynamical formalism is extended by setting the time constants of the Lorentzian terms to -l/e% and 1/(coil+ oN). This analysis is compared to the earlier proposed three-parameter (S~,S~,'c~) extended model free formalism with regard to the range of equivalence and the advantages of the sim-(Sf,Sn) and (Sf,SN) representations. Spectral density components are calculated plified two-parameter 2 2 2 2 and compared to those obtained from the spectral density analysis formalism. Protein relaxation data, commonly analyzed in terms of the two-parameter (S2,%) representation, may correspond to a dynamically heterogeneous behaviour that is more appropriately represented in terms of a fast limit order parameter and a second, lower frequency order parameter.

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