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Large-scale, Uniform DNA Network on 11-mercaptoundecanoic Acid Modified Gold (111) Surface: Atomic Force Microscopy Study

✍ Scribed by Yonghai Song; Li Wang; Lanlan Sun; Gang Wei; ZHIGUO LIU; Li Wang; Zhuang Li

Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 664 KB
Volume: 70
Category: Article
ISSN: 1059-910X
DOI: 10.1002/jemt.20436

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✦ Synopsis

Abstract

Large‐scale, uniform plasmid deoxyribonucleic acid (DNA) network has been successfully constructed on 11‐mercaptoundecanoic acid modified gold (111) surface using a self‐assembly technique. The effect of DNA concentration on the characteristics of the DNA network was investigated by atomic force microscopy. It was found that the size of meshes and the height of fibers in the DNA network could be controlled by varying the concentration of DNA with a constant time of assembly of 24 h. Microsc. Res. Tech., 2007. © 2007 Wiley‐Liss, Inc.

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## Abstract Immobilized DNA on preformed 11‐mercaptoundecanoic acids (MUDA) self‐assembled monolayers (SAMs) on a gold (111) surface was bound by a divalent cation bridges was imaged by atomic force microscopy (AFM). The DNA immobilization was attributed to the formation of ionic bridges between th