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Large-scale Top-down Proteomics of the Human Proteome: Membrane Proteins, Mitochondria, and Senescence

✍ Scribed by Catherman, Adam D.; Durbin, Kenneth R.; Ahlf, Dorothy R.; Early, Bryan P.; Fellers, Ryan T.; Tran, John C.; Thomas, Paul M.; Kelleher, Neil L.


Book ID
121445220
Publisher
The American Society for Biochemistry and Molecular Biology
Year
2013
Tongue
English
Weight
402 KB
Volume
12
Category
Article
ISSN
1535-9476

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Single residue mutations in proteins are known to affect protein stability and function. As a consequence, they can be disease associated. Available computational methods starting from protein sequence/structure can predict whether a mutated residue is or not disease associated and whether it is pro