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Large-Scale Synthesis of H-Antigen Oligosaccharides by Expressing Helicobacter pylori α1,2-Fucosyltransferase in Metabolically Engineered Escherichia coli Cells

✍ Scribed by Sophie Drouillard; Hugues Driguez; Eric Samain


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
109 KB
Volume
45
Category
Article
ISSN
0044-8249

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## Abstract __Two metabolically engineered__ Escherichia coli __strains have been constructed to produce the carbohydrate moieties of gangliosides GM2 (GalNAc__β__‐4(NeuAc__α__‐3)Gal__β__‐4Glc; Gal=galactose, Glc=glucose, Ac=acetyl) and GM1 (Gal__β__‐3GalNAc__β__‐4(NeuAc__α__‐3)Gal__β__‐4Glc. The G