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Large-scale production, purification and bioactivity assay of recombinant human interleukin-6 in the methylotrophic yeast Pichia pastoris

✍ Scribed by Hongbo Li; Yu Wang; Aimin Xu; Shiwu Li; Shouguang Jin; Donghai Wu


Book ID
109295764
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
239 KB
Volume
11
Category
Article
ISSN
1567-1356

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## Abstract __Microsomal cytochrome P450 monooxygenases of groups 1–3 are mainly expressed in the liver and play a crucial role in phase 1 reactions of xenobiotic metabolism. The cDNAs encoding human CYP2D6 and human NADPH‐P450 oxidoreductase (CPR) were transformed into the methylotrophic yeast__ P