Recombinant Production of Human Microsom
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Matthias Dietrich; Lisa Grundmann; Katja Kurr; Laura Valinotto; Tanja Saussele;
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Article
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2005
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John Wiley and Sons
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English
β 223 KB
π 1 views
## Abstract __Microsomal cytochrome P450 monooxygenases of groups 1β3 are mainly expressed in the liver and play a crucial role in phase 1 reactions of xenobiotic metabolism. The cDNAs encoding human CYP2D6 and human NADPHβP450 oxidoreductase (CPR) were transformed into the methylotrophic yeast__ P