✦ LIBER ✦

Large-scale efficacy trials of hepatitis B vaccines in the USA: Baseline data and protocols

✍ Scribed by Dr. Wolf Szmuness

Publisher: John Wiley and Sons
Year: 1979
Tongue: English
Weight: 867 KB
Volume: 4
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890040411

No coin nor oath required. For personal study only.

✦ Synopsis

The protocols of three placebo-controlled, randomized, double-blind clinical trials to assess the efficacy of an inactivated hepatitis B vaccine in dialysis patients and staff, and in male homosexuals are described. Based on the projected attack rates of HBV in the controls, the vaccine efficacy and rates of loss to follow-up, over three thousand participants followed for at least twelve months are required to prove the efficacy of the vaccine. The results of longterm baseline studies in these populations are also reviewed.

📜 SIMILAR VOLUMES

Multicenter trial on the efficacy of HBI

Multicenter trial on the efficacy of HBIG and vaccine in preventing perinatal hepatitis B. Final report

✍ Prof. A. R. Zanetti; P. Dentico; C. Del Vecchio Blanco; E. Sagnelli; E. Villa; P 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 473 KB 👁 2 views

## f. V), Italy In an attempt to interrupt perinatal transmission of hepatitis B, 92 infants born to HBsAg carrier mothers (49 to HBeAg-positive mothers, 30 to anti-HBe-positive with abnormally elevated ALT levels, and 13 to HBeAg/anti-HBe-negative mothers) received 0.5 ml/kg BW of HBIG at birth a