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Large-scale effects of transcriptional DNA supercoiling in Vivo

✍ Scribed by Andrey S. Krasilnikov; Alexei Podtelezhnikov; Alexander Vologodskii; Sergei M. Mirkin

Book ID
115539049
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
487 KB
Volume
292
Category
Article
ISSN
0022-2836

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Despite remarkable progress in genome science, we are still far from a clear understanding of how genomic DNA is packaged without entanglement into a nucleus, how genes are wrapped up in chromatin, how chromatin structure is faithfully inherited from mother to daughter cells, and how the differentia