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Langerhans cells arise from monocytes in vivo

✍ Scribed by Ginhoux, Florent; Tacke, Frank; Angeli, Veronique; Bogunovic, Milena; Loubeau, Martine; Dai, Xu-Ming; Stanley, E Richard; Randolph, Gwendalyn J; Merad, Miriam

Book ID: 109923215
Publisher: Nature Publishing Group
Year: 2006
Tongue: English
Weight: 505 KB
Volume: 7
Category: Article
ISSN: 1529-2908
DOI: 10.1038/ni1307

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## Background: Langerhans cell histiocytosis (lch) is a histiocytic disease, characterized by the lesional accumulation of dendritic langerhans cells together with t cells and eosinophils. the cause of this disease is unknown. langerhans cells are bone marrow-derived dendritic cells (dcs), which ca