Background. Because prostaglandin (PG) E2 has been identified in the bone lesions of Langerhans cell histiocytosis (LCH), we speculated that indomethacin, a potent PG inhibitor, may be useful in patients with symptomatic LCH involving the bony skeleton. Procedure. We used indomethacin to treat patie
Langerhans’ cell histiocytosis of the spine: use of MRI in guiding biopsy
✍ Scribed by G. R. Kaplan; A. Saifuddin; J. A. S. Pringle; M. H. Noordeen; M. H. Mehta
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 228 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0364-2348
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Langerhans' cell histiocytosis (LCH) is characterized by an accumulation and/or proliferation of cells with a Langerhans' cell (LC) phenotype. The aetiology and pathogenesis of LCH are unknown; it is suggested that LCH is caused by an immunological dysregulation. Production of cytokines is a central
## Abstract Twenty‐two patients with Langerhans cell histiocytosis (LCH) were managed in the UCLA Department of Radiation Oncology from 1974 to 1987. Their median age was 17 years (range 1–42 years) and median followup 4.5 years (range 1–13 years). Fourteen patients had disease localized to a bone